Clinical Trials
Explore actively recruiting clinical trials from ClinicalTrials.gov with patient-friendly summaries
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Search by condition, sponsor, research site, or NCT ID — e.g. breast cancer, Pfizer, Mayo Clinic, or NCT01234567
Showing 9 featured studies — search above to explore every recruiting trial
Phase 1 (Safety)NCT07878988
Phase 1 Study: Evaluating Treatment for Colorectal Cancer
Colorectal Cancer, Advanced/Metastatic Solid Tumor
Scottsdale, ArizonaAccepting Patients
About This Study
This is a first-in-human, Phase 1, multi-center, open-label study to characterize the safety, pharmacokinetics, pharmacodynamics
and preliminary anti tumor activity of LTZ-232 as monotherapy in adult participants with unresectable or metastatic colorectal cancer and other solid tumors failing standard therapies
Not specifiedNCT07875192
Studying Surgery for Prostate Cancer (diagnosis)
Prostate Cancer (Diagnosis)
Columbus, OhioAccepting Patients
About This Study
A Single-center Study of Robotic Prostatectomy Surgeries Performed using the Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in an Ambulatory Surgical Center Setting
ObservationalNCT07876349
Testing Treatment for Breast Cancer
Breast Cancer, Ovarian Cancer
New York, New YorkAccepting Patients
About This Study
The purpose of this research study is to test how well a new approach - using tools built into the electronic health record (EHR)- can help increase genetic testing for hereditary breast and ovarian cancer (HBOC) in women who have a family history that puts them at higher risk
The study will also look at what helps or gets in the way of using these tools in everyday clinical care
As part of this study, the investigators are also evaluating a website called RealRisks, which is designed to support patients in understanding their risk and making informed decisions about genetic testing
Phase 3 (Comparison)NCT06103513
Studying Treatment for Growth Disorders
Growth Disorders, Growth Failure
New York, New YorkAccepting Patients
About This Study
A prospective, randomized, open-label single-blinded study of 50 subjects with growth hormone deficiency, ages 5 to 15 years in which 25 subjects will initiate rhGH therapy at 0.3mg/kg/week and the remaining 25 subjects will initiate their rhGH treatment at 0.2 mg/kg/week for the first 12 months of treatment
Safety parameters, height velocity, and adult height prediction by bone age determination will be assessed at 4-month intervals for 1 year following the initiation of rhGH therapy
Phase 1 (Safety)NCT02013336
Phase 1 Study: Studying Treatment for Recurrent or Refractory Solid Tumors
Recurrent or Refractory Solid Tumors, Ewing Sarcoma
5 locations in Ohio, Oklahoma, Texas +1 more statesAccepting Patients
About This Study
This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide
The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide
ObservationalNCT05281445
Exploring the Role of Neuroactive Steroids in Tourette Syndrome
Tourette Syndrome in Children
Salt Lake City, UtahAccepting Patients
About This Study
Tourette syndrome (TS) is a disabling neurodevelopmental disorder characterized by motor and phonic tics
The studies proposed in this application will explore the endocrine mechanisms underlying two of the least well-understood biological characteristics of TS, namely its marked male predominance and stress susceptibility
In particular, our exploratory studies will characterize the steroid profile in TS-affected boys and girls to identify novel potential biomarkers and therapeutic targets for this disorder
Not specifiedNCT07878923
Comparing Treatment for Relapse Remitting Multiple Sclerosis
Relapse Remitting Multiple Sclerosis
Oklahoma City, OklahomaAccepting Patients
About This Study
This study will compare starting Ocrevus Zunovo soon after an active episode of relapsing multiple sclerosis (MS) with starting it later
Researchers want to learn whether starting treatment sooner reduces the number of MS relapses over 18 months
They will also study changes in immune cells, blood markers, disability, and MRI scans
Not specifiedNCT07877246
Studying Observational Study for Neuropsychiatric Disorders
Neuroinflammatory Disorders, Post-Infectious Neuropsychiatric Disorders
3 locations in California, Maryland, MassachusettsAccepting Patients
About This Study
Background:
Some brain or mental health conditions may be caused when a person s immune system attacks their own body
These are called immunologic neuropsychiatric disorders
In this natural history study, researchers want to see if they can find substances in the blood that can help them identify people with this kind of brain or mental illness
ObservationalNCT07879014
Evaluating Treatment for Rehabilitation Exercise
Rehabilitation Exercise
2 locations in Florida, New YorkAccepting Patients
About This Study
The goal of this randomized clinical trial is to access the following:
1
Compare the effectiveness of the QKP versus a standard rehabilitation protocol in improving postoperative pain control, ROM, and functional recovery following primary TKA
Assess whether the QKP reduces reliance on formal PT services