Clinical Trials

Explore actively recruiting clinical trials from ClinicalTrials.gov with patient-friendly summaries

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Search by condition, sponsor, research site, or NCT ID — e.g. breast cancer, Pfizer, Mayo Clinic, or NCT01234567

Showing 19 of 9 trials

Phase 2 (Efficacy)NCT07795749

Studying Treatment for Esophageal Cancer

Esophageal Carcinoma, Gastric Cancer (Diagnosis)

Orange, CaliforniaAccepting Patients
About This Study
This is a phase II open-label, basket clinical trial to assess the feasibility of systemic and Intraperitoneal chemotherapy in subjects with Gastrointestinal Malignancies with Peritoneal Carcinomatosis
These are subjects who have a proven primary carcinoma of the digestive tract.
ObservationalNCT07790718

Testing Treatment for Colon Polyp

Colon Polyp, Colorectal Carcinoma

2 locations in CaliforniaAccepting Patients
About This Study
This clinical trial evaluates the effects of exercise therapy on signs of colorectal cancer in colon tissue and blood in people who completed pelvic radiation therapy for prostate cancer
People who get radiation in the pelvic area have a higher chance of developing colon cancer years later
This is because radiation can cause new mutations and inflammation
Phase 2 (Efficacy)NCT07071961

Studying Treatment for Colorectal Cancer

Colorectal Cancer, Regorafenib

Houston, TexasAccepting Patients
About This Study
To learn about the effects of the drugs regorafenib and lorigerlimab on circulating tumor DNA (ctDNA) in patients with CRC and who have radiographic occult minimal residual disease (MRD) after completing standard-of-care therapy
ObservationalNCT06818877

Studying Treatment for Cerebral Palsy Children

Cerebral Palsy Children, Healthy Children

Omaha, NebraskaAccepting Patients
About This Study
This study is testing ways to help children with cerebral palsy (CP) improve how their hands work
Investigators want to see if brain activity using a virtual reality (VR) program can make their hands work better
The program is called Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)
ObservationalNCT07784348

Evaluating Treatment for ADHD

ADHD

Tallahassee, FloridaAccepting Patients
About This Study
Initial non-randomized trial of behavioral parent training (BPT) compared to central executive training (CET), followed by a randomized controlled trial of CET+BPT for young children with ADHD
ObservationalNCT07721662

Skin-to-skin Care Using the Skincubator: Feasibility and Safety Trial

Skin to Skin Care for Preterm Infants

Houston, TexasAccepting Patients
About This Study
The purpose of this study is to assess the impact of the Skincubator on average daily duration of Skin-to-skin Care (SSC), to assess the safety of Skincubator-supported SSC during NICU hospitalization, to evaluate feasibility and acceptability of the Skincubator among parents and clinical staff using the Acceptability of Intervention Measure (AIM) implementation framework to assess thermal stability during Skincubator-supported SSC and to assess changes in parental stress associated with Skincubator use during NICU hospitalization
Early Phase 1NCT07794956

Studying Treatment for Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment (MCI), Cognition

Tampa, FloridaAccepting Patients
About This Study
This randomized placebo-controlled clinical study, called the LpD3.5 Intervention Study in Older Adults (LISA), aims to evaluate whether a heat-inactivated postbiotic of human origin (LpD3.5) can serve as a non-pharmacological intervention to reduce gut permeability and inflammation in older adults with mild cognitive impairment (MCI)
The study will assess the effects of LpD3.5 supplementation on markers associated with gut health, inflammation, microbiome composition, and cognitive function
Participants aged 60 years or older with clinically diagnosed MCI will receive either LpD3.5 capsules or placebo capsules for 60 days, followed by a 30-day follow-up period
ObservationalNCT07796139

Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction

Patulous Eustachian Tube Dysfunction

Houston, TexasAccepting Patients
About This Study
The Eustachian tube connects the middle ear to the back of the nose and throat, providing ventilation of the middle ear
People with a patulous Eustachian tube perceive the tube stays open continuously
This can make a person's own voice and breathing sound unusually loud in the ear and can cause a feeling of fullness or blocked hearing
Phase 2 (Efficacy)NCT07795814

Studying Treatment for Heart Failure with Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

25 locations in Alabama, California, Illinois +15 more statesAccepting Patients
About This Study
This is a Phase 2 placebo-controlled study to evaluate the safety and tolerability of different doses of EDG-15400 in adults with heart failure with preserved ejection fraction (HFpEF)